Description
Description
Buy 4f-mph online
What Is 4F-ADB or 4f-MDMB-Binaca?
Buy 4f-mph online. 4F-MPH Powder (also known as4-Fluoromethylphenidate and 4-FMPH) is a stimulant drug. It acts as a higher potency dopamine reuptake inhibitor than the closely related methylphenidate.
4F-ADB or 4F-MDMB-Binaca is a synthetic cannabinoid that has been found in products marketed as “legal highs.” It’s an agonist of the CB1 receptor (EC50 = 7.39 nM), but it’s not clear whether it is specific to this target. 4F-ADB was created in order to avoid the banning of 4F-MPH, which is a similar compound.
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4-Fluoromethylphenidate was studied further along with other analogs of (±)-threo-methylphenidate (TMP) to assess their potential as anti-cocaine medications. 4F-MPH was reported as having an ED50 mg/kg of 0.26 (0.180.36), regarding its efficacy as a substitute for cocaine, and a relative potency of 3.33 compared to methylphenidate for the same purpose.
Another study found that in the threo-isomers of methylphenidate, the meta and para-substituted compounds with electron-withdrawing substituents tended to have increased binding potency. Compounds containing fluorine, chlorine, bromine, and methyl groups were reported to be more potent than methylphenidate. 4
F-MPH was reported as having the following values: [3H]WIN 35428 binding of 35.0 ± 3.0 (2) and [3H]dopamine 142 ± 2.0 (2).
4-Fluoromethylphenidate – WikipediaLegal status:
4-Fluoromethylphenidate is a Schedule I controlled substance in the US state of Alabama. As of 5 May 2017, 4-fluoromethylphenidate is a controlled substance in Canada.
Chemical and physical data
Formula: C14H18FNO2
Molar mass: 251.3 g/mol g·mol?1
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